Renewable energy has become the primary goal for the world's major countries in order to offset the negative effects of non-renewable energy. Today, we need bioenergy urgently to help our planet to be better for us and our offspring. For many biofuels, biomass is the best option; it can be converted chemically, physically or biologically to valuable output. Laccase enzymes are not only widely distributed in higher plants, bacteria, fungi and even insects, but they also have the magic stalk to convert waste into valuable and clean energy. Laccases are considered as environment friendly enzymes and widely used in different industrial fields because of their broad substrate specificity. Laccases are used for the production of different green fuels as ethanol and biogas using agricultural waste. They are also widely used as biocatalysts in the microbial fuel cell to produce bioelectricity and decontaminate waste water. This review focuses on the many advantages of green energy and laccase applications as green tools for clean fuel.