Dalmatian Sage (Salvia officinalis L.): A Review of Biochemical Contents, Medical Properties and Genetic Diversity
Martina GRDIŠA, Marija JUG-DUJAKOVIĆ, Matija LONČARIĆ, Klaudija CAROVIĆ-STANKO, Tonka NINČEVIĆ, Zlatko LIBER, Ivan RADOSAVLJEVIĆ, Zlatko SATOVIC
Pages: 69-78
Summary
Dalmatian sage (Salvia officinalis L.) represents one of the most significant medicinal autochthonous species in flora of eastern Adriatic coast and islands. It is evergreen outcrossing perennial subshrub with short woody stems that branch extensively and violet flowers. Apart from being native to Mediterranean karst of west Balkan and Apenine peninsula it is cultivated in numerous countries worldwide with Mediterranean and temperate continental climate. From the earliest times it has been used in traditional medicine in healing gingiva, mouth cavity and the sore throat, against bacterial and fungal infections, for wound treatment, memory enhancement, for treating common cold, against sweating, stomach inflammation, ulcer formation, etc. Its essential oil has also been used in preservation of food and as spice as it gives both specific aroma and promotes digestion of food. The essential oil is extremely complex mixture of different active ingredients; however, the thujones and camphor are the dominant compounds and are the parameter by which S. officinalis is distinguished from other Salvia species. The great variability of essential oil composition and yield has been detected depending on various factors such as genotype, environmental conditions, phenological stage, plant parts used for the extraction of essential oil and drying procedure. Molecular genetic analysis of S. officinalis is still limited and comprises the use of RAPD markers, AFLP and SSR markers in assessing mostly the genetic variability and structure of wild S. officinalis populations.
Keywords
Dalmatian sage, essential oil, Meditteranean, Salvia officinalis L., thujone
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