The effect of harvesting, H1 (Non- cut and uproot at 40 days after transplanting), H2 (harvest at 40 days and uproot at 55 days after transplanting), H3 (harvest at 40 and 55days after transplanting and uprooting 70 days after planting) and four rates (0, 10, 15 and 20 t ha[1]1 ) of poultry manure application on growth, yield and nutrient uptake of Celosia argentea was evaluated for two years. The trial was a 3 x 4 factorial laid out in a randomized complete block design (RCBD) in three replications. Poultry manure significantly p < 0.05) increased all the parameters above the control. H2 increased the number of leaves, branches and root length significantly in both years and nutrient uptake was the highest at 15 t ha-1 poultry manure application except for Ca which increased up to 20 t ha-1. N uptake (42.31 kg ha-1) was highest at H2 while P (9.43 kg ha-1), K (41.13 kg ha-1), Ca (34.33 mg 100g-1), Mg (19.07 mg 100g-1), Na (4.98 mg 100g-1) and Fe (1302.01 mg 100g-1) uptakes were highest at H3. The highest herbage yield (13.29 t ha-1 and 12.80 t ha-1) was produced at H2 in both years at 10 t ha-1 while seed yield (36.61 t ha-1) was the highest at H1 and 20 t ha-1 poultry manure.